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Saggy skin on the body caused by moderate weight loss or pregnancy can be improved through exercise. Any movement that builds muscle mass or tightens muscles can reduce the look of minor skin.
Pathology service at instituto lauro de souza lima (ilsl) - bauru (sp), brazil. Abstract: we report a case of granulomatous slack skin, a rare and indolent subtype.
Granulomatous slack skin is a condition characterized by the slow development of pendulous, lax skin, most commonly in the areas of the axillae and groin.
Nov 18, 2020 my chief resident presented a case to me enamored with his clinical diagnosis of granulomatous slack skin (gss).
Treatment options are based on the recommendations for cutaneous t- cell lymphoma and include topical steroids, surgical remvoval of skin folds, radiation therapy and chemotherapy.
In granulomatous slack skin syndrome, an extremely rare disorder, clonal cd4 + t cells elicit a reactive granulomatous response that destroys the elastic fibers, rendering skin slack, fibrotic, and inelastic (fig. Changes characteristic of mf are often found within the epidermis and papillary dermis, and the reticular dermis contains numerous histiocytes with multinucleated giant cells and elastophagocytosis.
Granulomatous slack skin (gss) is a rare cutaneous condition, a variant of lymphoma that typically presents in middle-aged adults. 735 it is a form of cutaneous t-cell lymphoma and a variant of mycosis fungoides.
Herein we describe a patient with simultaneous occurrence of granulomatous slack skin type mycosis fungoides and a sarcoid‐like reaction. The question remains open whether this represents the so‐called sarcoidosis‐lymphoma syndrome or, more likely, granulomatous slack skin mf associated with a sarcoid‐like reaction of “foreign body.
/ granulomatous mycosis fungoides and granulomatous slack skin a multicenter study of the cutaneous lymphoma histopathology task force group of the european organization for research and treatment of cancer (eortc).
This article reviews its literature on the etiology, clinical findings, and treatment of granulomatous slack skin disease. Gov] mckee's pathology of the skin is the most complete, in-depth resource on dermatopathology, covering etiology, pathogenesis, disease mechanisms, and recent genetic, molecular, and basic science data.
Granulomatous slack skin is extremely rare, has an indolent clinical course, and appears with pendulous folds of skin, usually in the axilla or groin. Folliculotropic mf is a variant that preferentially involves hair follicles and manifests as grouped acneiform papules or plaques on the head and neck.
Type/sub-type these problems reverse on their own after the medication is stopped.
Aug 28, 2017 granulomatous slack skin syndrome is a rare variant of cutaneous t-cell lymphoma (mycosis fungoides).
Rare associations of granulomatous dermatitis with leukaemia [6], lymphoma, breast cancer, hypopharyngeal squamous cell carcinoma and endometrial neoplasia have been reported. How is granulomatous dermatitis treated? granulomatous dermatitis typically flares and remits. Successful treatments have included: topical steroids; hydroxychloroquine; dapsone.
We report an 11-year follow-up of a case of granulomatous slack skin. The patient was first treated surgically followed by a rapid relapse.
Granulomatous slack skin (gss) is a very rare subtype of mycosis fungoides (mf), with fewer than 50 cases already reported. It is 1 of the 3 variants of mf, along with folliculotropic mf and pagetoid reticulosis (world health organization-european organization for research and treatment of cancer, 2018).
For improving the odds of diagnosing atypical cases of mf, the authors offer sage advice: maintain a high index of suspicion; perform a meticulous full body skin examination; discontinue topical steroids at least two weeks prior to obtaining skin biopsies; perform multiple biopsies from a variety of lesions;.
Granulomatous slack skin is a very rare disorder that may be associated with mycosis fungoides, hodgkin’s disease, or acute myeloid leukemia. The cause of the condition is generally unknown the skin signs and symptoms may be treated using topical applications, medications, and phototherapy.
Granulomatous slack skin syndrome is a rare variant of cutaneous t-cell lymphoma (mycosis fungoides). It is characterized clinically by redundant skin folds, which show a predilection towards flexural areas such as the axilla and the groin. Histologically, it shows a granulomatous t-cell infiltrate and loss of elastic tissue.
Granulomatous slack skin - seven years follow-up of a case with features of parapsoriasis en plaques, muscle involvement, granulomatous vasculitis, and necrobiotic changes.
Granulomatous slack skin (gss) is a rare and indolent subtype of mycosis fungoides (mf). It affects mainly adult males in the third and fourth decades of life (mean.
Granulomatous slack skin (gss) is a rare cutaneous disorder characterized by the evolution of circumscribed erythematous loose skin masses, especially in the body folds, and histologically by a loss of elastic fibers and granulomatous t-cell infiltrates. This disease is often associated with preceding or successive lymphoproliferative malignancies, especially mycosis fungoides (mf) and hodgkin's disease (hd).
My chief resident presented a case to me enamored with his clinical diagnosis of granulomatous slack skin (gss). Although i was delighted that he considered the disorder, i explained why i thought these inguinal and submammary pink-white subtly atrophic plaques were more likely lichen scler.
Dec 31, 2012 granulomatous slack skin is a very rare subtype of t-cell cutaneous lymphoma, characterized by the slow development of cutaneous sagging,.
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